Thank you for participating!

Thank you to all who contributed to the National Heart, Lung, and Blood Institute (NHLBI) Strategic Visioning Forum. Ultimately, over 1,000 ideas were submitted, with more than 42,000 votes. This remarkable response exceeded expectations and provided a wealth of ideas to draw upon as NHLBI moves forward. Please visit the NHLBI Strategic Visioning page to find out more about the NHLBI Strategic Visioning process.


Welcome to the National Heart, Lung, and Blood Institute (NHLBI) Strategic Visioning Forum. The Institute is gathering ideas for the most compelling scientific priorities in the four NHLBI Strategic Goals to address over the next decade.

(@nhlbiforumadministrator) kudos icon +

Goal 1: Promote Human Health

Rejuvenating Old Hearts and Lungs

Is there a true "mechanome" affecting normal heart function that could be studied to uncover important mechanically-stimulated pathways relevant to tissue development, maintenance, and repair in vivo?
Are there mechanomics that predict and control fundamental biological processes linked to the body's natural healing and regeneration machinery? What if we could leverage 3D tissue engineering advances to rejuvenate aging... more »

Voting

27 net votes
43 up votes
16 down votes
Active
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Goal 3: Advance Translational Research

Novel therapeutics for patients with severe acute lung injury

Can novel therapeutics including cell-based therapy be tested in patients with severe acute lung injury (P/F <200) and shock (need for vasopressors) since these are the patients with the highest mortality (> 30%) based on NHLBI ARDS Network data?

Voting

1 net vote
1 up votes
0 down votes
Active
(@nhlbiforumadministrator) kudos icon +

Goal 1: Promote Human Health

Basic research in glycobiology is urgently needed

There are two areas in which glycobiology has been very successful: technology development and disease correlation. Through efforts exemplified by the CFG, major strides in mass spectroscopy and the creation of novel technologies for probing glycan-protein interactions (e.g. glycan microarrays) have been seen. Likewise, the success of the Programs of Excellence in Glycoscience and those of us focused on disease have also... more »

Voting

3 net votes
3 up votes
0 down votes
Active
(@chriscage) kudos icon +

Goal 2: Reduce Human Disease

Address bias of doctors treating obese patients

Twice I was allowed to develop severe heart failure symptoms that required hospitalization to treat because my primary care physician assumed that my ONLY problem was that I am fat.

Every doctor knows that obesity can lead to the development of diabetes, heart diseases, joint damage and yet too many doctors on the frontlines just say: You're fat go diet.

My first experience with this was when I was first diagnosed... more »

Voting

5 net votes
21 up votes
16 down votes
Active
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Goal 3: Advance Translational Research

Personalized Medicine thru CV bioinformation/tissue repository

There is a need to establish virtual CV biologic tissues and a bioinformational repository for specific CV diseases, including congenital cardiovascular malformations, genetic or other unique cardiomyopathies, such as stress cardiomyopathy and giant cell myocarditis.

Voting

-13 net votes
10 up votes
23 down votes
Active
(@neilblumberg) kudos icon +

Goal 2: Reduce Human Disease

Reducing the toxicity and morbidity of blood transfusions

Transfusion is the most commonly prescribed inpatient procedure. Blood transfusions have been shown in randomized trials to predispose to novel side effects. These include nosocomial infection, multi-organ failure, thrombosis and mortality due to these causes. Even in an era of more restrictive transfusion, there is an urgent need to understand and mitigate the mechanism(s) of these effects. Some patients will always... more »

Voting

-3 net votes
22 up votes
25 down votes
Active
(@popkin) kudos icon +

Goal 1: Promote Human Health

Evaluation of large-scale regulatory efforts in the US and elsewhere

A number of cities(e.g Berkeley), states and countries (e.g Mexico's SSB tax, Chiles SSB and soon marketing controls and food package front of package label) will go into effect. Rigorous evaluations of the efforts will provide some sense of their potential to effect food purchase and dietary pattern and ultimately cardiometaboiic changes. Serious rigorous independent evaluations are needed to learn if these options--pushed... more »

Voting

22 net votes
42 up votes
20 down votes
Active
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Goal 3: Advance Translational Research

Pathways for Developing Pediatric Medical Devices

There is a need to develop innovative means to attract appropriate medical device industries to develop devices for the treatment and/or diagnosis of cardiovascular, pulmonary, or blood diseases in young children.

Voting

13 net votes
23 up votes
10 down votes
Active